原著論文

シンギュラリティ生物学　成果データベース　SSBD

A02-1計画班（大浪班）で運用するSSBD1では、シンギュラリティ生物学のデータマネジメントの立場から、
成果論文および共有いただいたデータをまとめた専用のデータポータル2を運用しています。成果論文を主にPubMed3およびPMC4から1)助成番号、2)研究者名と所属をもとに絞り込み、研究班などの情報を付与し、SSBDのデータへのリンクとともに提供しています。現在2,265編の論文情報と50プロジェクトのデータが収集されています。データ公開のご要望についても引き続き受け付けております。

1 SSBD https://ssbd.riken.jp/
2 Papers related to Singularity Biology project https://ssbd.riken.jp/singbio/
3 PubMed https://pubmed.ncbi.nlm.nih.gov/
4 PubMed Central https://www.ncbi.nlm.nih.gov/pmc/

シンギュラリティ生物学データベースの使い方

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主な雑誌論文　総計959報

計画 A01-1渡邉班　合計70報

  1. Kaneshiro J, Shioi G, Okamoto K, Onami S, *Watanabe TM. “Improvement in image quality via the pseudo confocal effect in multidirectional digital scanned laser light-sheet microscopy.” Opt Express 29: 24278-24288 (2021).
  2. *Mizushima R, Inoue K, Fujiwara H, Iwane AH, *Watanabe TM, *Kimura A. “Multiplexed 129Xe HyperCEST MRI Detection of Genetically Reconstituted Bacterial Protein Nanoparticles in Human Cancer Cells.” Contrast Media Mol Imaging 12: 2020:5425934 (2020).
  3. Matsumoto K, Mitani TT, Horiguchi SA, Kaneshiro J, Murakami TC, Mano T, Fujishima H, Konno A, Watanabe TM, Hirai H, *Ueda HR. ”Advanced CUBIC tissue clearing for whole-organ cell profiling.” Nat Protoc 14: 3506-37 (2019).
  4. Kaneshiro J, Okada Y, Shima T, Tsujii M, Imada K, Ichimura T, *Watanabe TM. “Second harmonic generation polarization microscopy as a tool for protein structure analysis.” Biophys Physicobiol 16: 147-57 (2019).
  5. Nishiyama M, Namita T, Kondo K, Yamakawa M, *Shiina T.“Ring-array photoacoustic tomography for imaging human finger vasculature.” J Biomed Opt 24: 1-12 (2019).

計画 A01-2永井班　合計80報

  1. Ichimura T, Kakizuka T, Horikawa K, Seiriki K, Kasai A, Hashimoto H, Fujita K, Watanabe TM, *Nagai T. “Exploring rare cellular activity in more than one million cells by a transscale scope.” Sci Rep 11: 16539 (2021).
  2. Shinoda H, Kai L, Nakashima R, Wazawa T, Noguchi K, Matsuda T, *Nagai T. “Acid-Tolerant Reversibly Switchable Green Fluorescent Protein for Super-resolution Imaging under Acidic Conditions.” Cell Chem Biol 26: 1469-79 (2019).
  3. Oketani R, Suda H, Uegaki K, Kubo T, Matsuda T, Yamanaka M, Arai Y, Smith N, Nagai T, *Fujita K. “Visible-wavelength two-photon excitation microscopy with multifocus scanning for volumetric live-cell imaging.”J. Biomed. Opt. 25: 014502 (2019).
  4. Endo M, Iwawaki T, Yoshimura H, *Ozawa T. “Photocleavable Cadherin Inhibits Cell-to-cell Mechanotransduction by Light.”ACS Chem Biol 14: 2206-14 (2019).
  5. Takenouchi O, Yoshimura H, *Ozawa T. “Unique Roles of β-Arrestin in GPCR Trafficking Revealed by Photoinducible Dimerizers.” Sci Rep 8: 677 (2018).

計画 A01-3城口班　合計12報

  1. Jin J§, Ogawa T§, Hojo N, Kryukov K, Shimizu K, Ikawa T, Imanishi T, Okazaki T, *Shiroguchi K. (§equally contributed) “Robotic data acquisition with deep learning enables cell image-based prediction of transcriptomic phenotypes” Proc Natl Acad. Sci U S A 120 (1): e2210283120 (2022).
  2. Jin J, Yamamoto R, Takeuchi T, Cui G, Miyauchi E, Hojo N, Ikuta K, Ohno H, *Shiroguchi K. “High-throughput identification and quantification of single bacterial cells in the microbiota.” Nat Commun 13: 863 (2022). 
  3. *Kimura S, Nakamura Y, Kobayashi N, Shiroguchi K, Kawakami E, Mutoh M, Takahashi-Iwanaga H, Yamada T, Hisamoto M, Nakamura M, Udagawa N, Sato S, Kaisho T, Iwanaga T, *Hase K. “Osteoprotegerin-dependent M cell self-regulation balances gut infection and immunity.” Nat Commun 11:234 (2020).
  4. Miyamoto C, Kojo S, Yamashita M, Moro K, Lacaud G, Shiroguchi K, Taniuchi I, *Ebihara T. “Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation.” Nat Commun 10:447 (2019).

計画 A02-1大浪班 合計19報

  1. Nozaki T, Shinkai S, Ide S, Higashi K, Tamura S, Shimazoe MA, Nakagawa M, Suzuki Y., Okada Y, Sasai M, Onami S, Kurokawa K, Iida S, *Maeshima K.“Condensed but liquid-like domain organization of active chromatin regions in living human cells.”Sci Adv 11, eadf1488 (2023).
  2. Kyoda K, Ho KHL, Itoga H, Tohsato Y, *Onami S. ”BD5: an open HDF5-based data format to represent quantitative biological dynamics data.” bioRxiv (2020).
  3. *Shinkai S, Nakagawa M, Sugawara T, Togashi Y, Ochiai H, Nakato R, Taniguchi Y, *Onami S. ”PHi-C: deciphering Hi-C data into polymer dynamics.”NAR Genom Bioinform 2: lqaa020(2020).
  4. *Shinkai S, Sugawara T, Miura H, Hiratani I, *Onami S. ”Michrorheology for Hi-C data reveals the spectrum of the dynamic 3D genome organization.” Biophys J 118: 2220-8(2020).
  5. Onoue Y, Kyoda K, Kioka M, Baba K, Onami S, *Koyamada K. ” Development of an integrated visualization system for phenotype character networks.” IEEE Pacific Visualization Symposium 21-5 (2018).

計画 A02-2小松崎班　合計57報

  1. Sattari S, Basak U, James R, Perrin L, Crutchfield J, *Komatsuzaki T. “Modes of information flow in collective cohesion.” Sci Adv, 8: 6 (2022).
  2. Basak US, Sattari S, Horikawa K, *Komatsuzaki T. Inferring Domain of Interactions among Particles from Ensemble of Trajectories. Phys. Rev. E, Accepted (2020).
  3. Tabata K, *Nakamura A, Honda J, Komatsuzaki T, “A bad arm existence checking problem: How to utilize asymmetric problem structure?” Mach Learn 109: 327-72 (2020).
  4. *Komatsuzaki T, *Pressé S, *Senet P “Deciphering Molecular Complexity in Dynamics and Kinetics – From the Single Molecule to the Single Cell Level.” J Phys Chem B 123: 6387-88 (2019).
  5. Helal KM, Taylor JN, Cahyadi H, Okajima A, Tabata K, Itoh Y, Tanaka H, Fujita K, *Harada Y, *Komatsuzaki T. “Raman spectroscopic histology using machine learning for nonalcoholic fatty liver disease.” FEBS Lett 593: 2535–44 (2019).

計画 A03-1坂内班 合計60報

  1. Okuzumi, A, Hatano, T, Matsumoto, G, Nojiri, S, Ueno, S, Imamichi Y, Kimura, H, Kakuta, S, Kondo, A, Fukuhara, T, Li, Y, Funayama, M, Saiki, S, Taniguchi, D, Tsunemi, T, McIntyre, D, Gérardy, J, Mittelbronn, M, Krüger, R, Uchiyama, Y, Nukina, N, *Hattori, N.“Propagative α-synuclein seeds as serum biomarkers for synucleinopathies.”Nat Medicine 29, 1448–1455 (2023).
  2. *Hiroshima M, Yasui M, Ueda M. “Large-scale single-molecule imaging aided by artificial intelligence.” Microscopy (Oxf) 69: 69-78, (2020).
  3. *Bannai H, Niwa F, Sakuragi S, Mikoshiba K. “Inhibitory synaptic transmission tuned by Ca2+ and glutamate through the control of GABAAR lateral diffusion dynamics.” Dev Growth Differ doi.org/10.1111/dgd.12667 (2020).
  4. Soeda Y, Saito M, Maeda S, Ishida K, Nakamura A, Kojima S, *Takashima A. “Methylene blue inhibits formation of tau fibrils but not of granular tau oligomers: A plausible key to understanding failure of a clinical trial for Alzheimer’s disease.” J Alzheimers Dis 68:1677-86 (2019).

計画 A03-2堀川班　合計31報

  1. Maruhashi T, Sugiura D, Okazaki IM, Shimizu K, Maeda TK, Ikubo J, Yoshikawa H, Maenaka K, Ishimaru N, Kosako H, Takemoto T, *Okazaki T. “Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity.” Immunity 55(5): 912-924 (2022).
  2. Kakizuka T, Hara Y, Ohta Y, Mukai A, Ichiraku A,AraiY, Ichimura T,NagaiT, *Horikawa K., Cellular logics bringing the symmetry breaking in spiral nucleation revealed by trans-scale imaging. bioRxiv, doi:10.1101/2020.06.29.176891 (2020).
  3. Iida H, Furukawa Y, Teramoto M, Suzuki H, Takemoto T, Uchikawa M, *Kondoh H. “Sox2 gene regulation via the D1 enhancer in embryonic neural tube and neural crest by the combined action of SOX2 and ZIC2.” Genes Cells 25:242-56 (2020).
  4. Yamamoto S, Uchida Y, Ohtani T, Nozaki E, Yin C, Gotoh Y, Yakushiji‐Kaminatsui N, Higashiyama T, Suzuki T, Takemoto T, Shiraishi Y, *Kuroiwa A “Hoxa13 regulates expression of common Hox target genes involved in cartilage development to coordinate the expansion of the autopodal anlage.” Dev Growth Differ 61:228-51 (2019).
  5. Morishima M, Horikawa K. *Funaki M. “Cardiomyocytes cultured on mechanically compliant substrates, but not on conventional culture devices, exhibit prominent mitochondrial dysfunction due to reactive oxygen species and insulin resistance under high glucose.” PLoS One 13: e0201891 (2018).

計画 A03-3橋本班　合計48報

  1. Nagai Y, Kisaka Y, Nomura K, Nishitani N, Andoh C, Koda M, Kawai H, Seiriki K, *Nagayasu K, Kasai A, Shirakawa H, Nakazawa T, Hashimoto H, *Kaneko S. “Dorsal raphe serotonergic neurons preferentially reactivate dorsal dentate gyrus cell ensembles associated with positive experience.” Cell Rep 42: 112149 (2023).
  2. Kawano S, Baba M, Fukushima H, Miura D, Hashimoto H, Nakazawa T. “Autism-associated ANK2 regulates embryonic neurodevelopment.” Biochem Biophys Res Commun 605:45-50 (2022).
  3. Tanuma M, *Kasai A, Bando K, Kotoku N, Harada K, Minoshima M, Higashino K, Kimishima A, Arai M, Ago Y, Seiriki K, Kikuchi K, Kawata S, Fujita K, *Hashimoto H. “Direct visualization of an antidepressant analog using surface-enhanced Raman scattering in the brain.” JCI Insight, 5:e133348 (2020).
  4. Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, Furuse T, Shibuya H, Yasuda Y, Yamamori H, Fujimoto M, Nagayasu K, Yamamoto K, Kitagawa K, Miura H, Gotoda-Nishimura N, Igarashi H, Hayashida M, Baba M, Kondo M, Hasebe S, Ueshima K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Iguchi T, Sato M, Tamura M, Wakana S, Yoshiki A, Watabe AM, Okano H, Takuma K, Hashimoto R, *Hashimoto H, *Nakazawa T. “Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes.” Nat Commun 11: 859 (2020).
  5. Seiriki K, *Kasai A, Nakazawa T, Niu M, Naka Y, Tanuma M, Igarashi H, Yamaura K, Hayata-Takano A, Ago Y, *Hashimoto H. ”Whole-brain block-face serial microscopy tomography at subcellular resolution using FAST.” Nat Protoc 14: 1509-29 (2019).

計画 A03-4岡崎班　合計52報

  1. Sugiura D, Okazaki IM, Maeda TK, Maruhashi T, Shimizu K, Arakaki R, Takemoto T, Ishimaru N, *Okazaki T. “PD-1 agonism by anti-CD80 inhibits T cell activation and alleviates autoimmunity.” Nat Immun 23: 399-410 (2022).
  2. Shimizu K, Sugiura D, Okazaki IM, Maruhashi T, Takegami Y, Cheng C, Ozaki S, *Okazaki T. “PD-1 imposes qualitative control of cellular transcriptomes in response to T cell activation.” Mol Cell 77: 937-50 (2020).
  3. Okamura H, Okazaki IM, Shimizu K, Maruhashi T, Sugiura D, Mizuno R, and *Okazaki T. “PD-1 aborts the activation trajectory of autoreactive CD8+ T cells to prohibit their acquisition of effector functions.” J Autoimmun 105: 102296  (2019).
  4. Sugiura D, Maruhashi T, Okazaki IM, Shimizu K, Maeda TK, Takemoto T, and *Okazaki T. “Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses.” Science, 364: 558-66, (2019).
  5. Nagai M, Noguchi R, Takahashi D, Morikawa T, Koshida K, Komiyama S, Ishihara N, Yamada T, Kawamura YI, Muroi K, Hattori K, Kobayashi N, Fujimura Y, Hirota M, Matsumoto R, Aoki R, Tamura-Nakano M, Sugiyama M, Katakai T, Sato S, Takubo K, Dohi T, *Hase K. “Fasting-Refeeding Impacts Immune Cell Dynamics and Mucosal Immune Responses.”Cell. 178: 1072-87, (2019).

公募A01班　合計152報

  1. *Hanaoka K, Iwaki S, Yagi K, Myochin T, Ikeno T, Ohno H, Sasaki E, Komatsu T, Ueno T, Uchigashima M, Mikuni T, Tainaka K, Tahara S, Takeuchi S, Tahara T, Uchiyama M, Nagano T, *Urano Y. “General design strategy to precisely control the emission of fluorophores via a twisted intramolecular charge transfer (TICT) process.” J Am Chem Soc 144: 19778 (2022).
  2. Liu N, *Matsumura H, Kato T, Ichinose S, Takada A, Namiki T, Asakawa K, Morinaga H, Mohri Y, De Arcangelis A, Geroges-Labouesse E, *Nanba D, *Nishimura, EK. “Stem cell competition orchestrates skin homeostasis and ageing.” Nature 568: 344-350 (2019).
  3. Orioka M, Eguchi M, Mizui Y, Ikeda Y, Sakama A, Li Q, *Yoshimura H, Ozawa T, Citterio D, *Hiruta Y. “A Series of Furimazine Derivatives for Sustained Live-cell Bioluminescence Imaging and Application to the Monitoring of Myogenesis at Single-cell Level.” Bioconjug. Chem., 33: 496-504 (2022).
  4. Hirasawa T, Tachi K, Miyashita M, Okawa S, Kushibiki T, *Ishihara M. “Spectroscopic photoacoustic microscopic imaging during single spatial scan using broadband excitation light pulses with wavelength-dependent time delay.” Photoacoustics 26: 100364 (2022).
  5. Satoh AO, Fujioka Y, Kashiwagi S, Yoshida A, Fujioka M, Sasajima H, Nanbo A, Amano M, *Ohba Y. “Interaction between PI3K and the VDAC2 channel tethers Ras-PI3K-positive endosomes to mitochondria and promotes endosome maturation.” Cell Rep 42: 112229 (2023).
  6. Ugawa M, *Ota S. “High-speed 3D imaging flow cytometry with optofluidic spatial transformation.” Biomed Opt Express 13: 3647-3656 (2022).
  7. Jahan A, Akter MT, Takemoto K, Oura T, Shitara A, Semba S, Nezu A, Suto S, Nagai T, Tanimura A. “Insertion of circularly permuted cyan fluorescent protein into the ligand-binding domain of inositol 1,4,5-trisphosphate receptor for enhanced FRET upon binding of fluorescent ligand” Cell calcium 108: 102668 (2022).
  8. Oe M, Suzuki K, Miki K, Mu H, Ohe K. “Steric Control in Activator-Induced Nucleophilic Quencher Detachment-Based Probes: High-Contrast Imaging of Aldehyde Dehydrogenase 1A1 in Cancer Stem Cells.” ChemPlusChem 87: e220200319 (2022).
  9. Hosokawa T, Tanaka S, Mori T, Baba Y, *Katayama Y “Quiescent B cells acquire sensitivity to cell cycle arresting agents by B cell receptor stimulation” Bio Pharm Bull 45: 847-850 (2020).

公募A02班 合計25報

  1. *冨樫 祐一, マイクロマシン集団の力学的相互干渉：「シンギュラリティ細胞」のモデルとして. 第64回システム制御情報学会研究発表講演会講演論文集 (2020).
  2. Handa T, Harada A, Maehara K, Sato S, Nakao M, Goto N, Kurumizaka H, *Ohkawa Y, *Kimura H.“Kimura H.: Chromatin integration labeling for mapping DNA-binding proteins and modifications with low input.” Nat Protoc 215: 3334-3360 (2020).
  3. Murata O, Shindo Y, Ikeda Y, Iwasawa N, *Citterio D, *Oka K, *Hiruta Y. “Near-Infrared Fluorescent Probes for Imaging of Intracellular Mg2+ and Application to Multi-Color Imaging of Mg2+, ATP, and Mitochondrial Membrane Potential.” Anal Chem 92:966-74 (2020).

公募A03班 合計392報

  1. Fujioka Y, Kashiwagi S, Yoshida A, Satoh AO, Fujioka M, Amano M, Yamauchi Y and Ohba Y. “A method for the generation of pseudovirus particles bearing SARS coronavirus spike protein in high yields.” Cell Struct Funct 47: 43-53 (2022).
  2. Jiang H, Kimura T, Hai H, Yamamura R, *Sonoshita M. “Drosophila as a toolkit to tackle cancer and its metabolism.” Frontier Onco 12: 982751 (2022).
  3. Yoshizawa K, Matsura A, Shimada M, Ishida-Ishihara S, Sato F, Yamamoto T, Yaguchi K, Kawamoto E, Kuroda T, Matsuo K, Tamaoki N, Sakai R, Shimada Y, Mishra M, and *Uehara R. “Tetraploidy-linked sensitization to CENP-E inhibition in human cells” Mol Onco In press (2023).
  4. Inoue M, Takeuchi A, Manita S, Horigane S-I, Sakamoto M, Kawakami R, Yamaguchi K, Otomo K, Yokoyama H, Kim R, Yokoyama T, Takemoto-Kimura S, Abe M, Okamura M, Kondo Y, Quirin S, Ramakrishnan C, Imamura T, Sakimura K, Nemoto T, Kano M, Fujii H, Deisseroth K, Kitamura K, *Bito H. “Rational engineering of XCaMPs, a multicolor GECI suite for in vivo imaging of complex brain circuit dynamics.” Cell 177: 1346-1360 (2019).
  5. Arii J, Takeshima K, Maruzuru Y, Koyanagi N, Nakayama Y, Kato A, Mori Y, *Kawaguchi Y. “Role of the arginine cluster in the disordered domain of Herpes Simplex Virus 1 UL34 for the recruitment of ESCRT-III for viral primary envelopment.” J. Virol 96: e0170421 (2022).
  6. Akutsu T, Mori T, Nakamura N, Kozawa S, Ueno Y, Sato TN. “On the complexity of tree edit distance with variables.” LPICS 44: 1-14 (2022).
  7. Perez CAG, Adachi S, Nong QD, Adhitama N, Matsuura T, Natsume T, Wada T, Kato Y, Watanabe H. “Sense-overlapping lncRNA as a decoy of translational repressor protein for dimorphic gene expression.” PLoS Genet 17: e1009683 (2021).
  8. Kalfaoglu B, Almeida-Santos J, Tye CA, Satou Y, *Ono M. “T-cell hyperactivation and paralysis in severe COVID-19 infection revealed by single-cell analysis.” bioRxiv 2020.05.26.115923 (2020).
  9. *Kubo M, Nagashima R, Kurihara M, Kawakami F, Maekawa T, Eshima K ,Ohta E, Kato H, Obata F. “Leucine-Rich Repeat Kinase 2 Controls Inflammatory Cytokines Production through NF-κB Phosphorylation and Antigen Presentation in Bone Marrow-Derived Dendritic Cells.” Int J Mol Sci 21: 1890 (2020).
  10. Miyamoto K, Hayabuchi H, Tokifuji Y, Ando M, Onishi N, Okamura T, Yoshimura A, *Chikuma S　“A Protein Kinase D inhibitor suppresses AKT on T cells and antagonizes cancer immunotherapy by Anti-PD-1.”　Int Immunol 16: dxac035 (2022).
  11. Akter E, Tasaki Y, Mori Y, Nakai K, Hachiya K, Lin H, Konno M, Kamasaki T, Tanabe K, Umeda Y, Yamano S, Fujita Y, *Kon S. “Non-degradable autophagic vacuoles are indispensable for cell competition.” Cell Rep 40: 111292 (2022).
  12. Matsumoto R, Suga H, Aoi T, Bando H, Fukuoka H, Iguchi G, Narumi S, Hasegawa T, Muguruma K, Ogawa W, Takahashi Y. “Congenital pituitary hypoplasia model demonstrates hypothalamic OTX2 regulation pf pituitary progenitor cells.” J Clin Investi 130, 641-654 (2020).
  13. Shibata AC, Ueda HH, Eto K, Onda M, Sato A, Ohba T, Nabekura J, *Murakoshi H. “Photoactivatable CaMKII induces synaptic plasticity in single synapses.” Nat Commun 12: 751 (2021).
  14. Uno W, Ofuji K, Wymeersch F. J, *Takasato, M. “In vitro induction of prostate buds from murine urogenital epithelium in the absence of mesenchymal cells.” Dev Biol 498: 49–60 (2023).
  15. Maeda J, Minamihisamatsu T, Shimojo M, Zhou X, Ono M, Matsuba Y, Ji B, Ishii H, Ogawa M, Akatsu H, Kaneda D, Hashizume Y, Robinson JL, Lee VMY, Saito T, Saido TC, Troganowski JQ, Zhang MR, Suhara T, Higuchi M, *Sahara N. “Distinct microglial response against Alzheimer’s amyloid and tau pathologies characterized by P2Y12 receptor.” Brain Commun 3: fcab011 (2021).
  16. Senoo H, Kamimura Y, Kimura R, Nakajima A, Sawai S, Sesaki H, *Iijima M “Phosphorylated Rho-GDP directly activates mTORC2 kinase towards AKT through dimerization with Ras-GTP to regulate cell migration.” Nat Cell Biol 21:867 – 78 (2019).
  17. Tsai C.J, Nagata T, Liu C, Suganuma T, Kanda T, Miyazaki T, Liu K, Saitoh T, Nagase H, Lazarus M, Vogt K, Yanagisawa M, *Hayashi Y. “Cerebral capillary blood flow upsurge during REM sleep is mediated by A2A receptors.” Cell Rep 17: 109558 (2021).
  18. Maeda F, Kato A, Takeshima K, Shibazaki M, Sato R, Shibata T, Miyake K, Kozuka-Hata H, Oyama M, Shimizu E, Imoto S, Miyano S, Adachi S, Natsume T, Takeuchi K, Maruzuru Y, Koyanagi N, Arii J, *Kawaguchi Y. “Role of the Orphan Transporter SLC35E1 in the Nuclear Egress of Herpes Simplex Virus 1.” J Virol 96: e0030622 (2022).
  19. Tanno A, Tokutsu R, Arakaki Y, Ueki N, Minagawa J, Yoshimura K, Hisabori T, Nozaki H, *Wakabayashi K. “The four-celled Volvocales green alga Tetrabaena socialis exhibits weak photobehavior and high-photoprotection ability.” PLoS ONE 16: e0259138 (2021).
  20. Kato S, Maeda Y, Sugiyama D, Watanabe K, *Nishikawa H, *Hinohara K. “The cancer epigenome: Non-cell autonomous player in tumor immunity.” Cancer Sci 114: 730-740 (2023).
  21. *Ono D, Wang H, Hung J.C, Wang T.H, Kon N, Yamanaka A, Li Y, Sugiyama T. “Network-driven intracellular cAMP coordinates circadian rhythm in the suprachiasmatic nucleus.” Sci Adv 9: 1 (2023).
  22. *Enomoto M, Takemoto D, *Igaki T. “Interaction between Ras and Src clones causes interdependent tumor malignancy via Notch signaling in Drosophila.” Dev Cell 56: 2223-2236 (2021).
  23. Oginuma M, Nishida M, Ohmura-Adachi T, Abe K, Ogamino S, Mogi C, Matsui N, *Ishitani T. “Rapid reverse genetics systems for Nothobranchius furzeri, a suitable model organism to study vertebrate aging.” Sci Rep 12: 11628 (2022).
  24. Kobayashi A, Hamada M, Yoshida MA, Kobayashi Y, Tsutsui N, Sekiguchi T, Matsukawa Y, Maejima S, Gingell JJ, Sekiguchi S, Hamamoto A, Hay DL, Morris JF, Sakamoto T, *Sakamoto H. “Vasopressin-oxytocin-type signaling is ancient and has a conserved water homeostasis role in euryhaline marine planarians.” Sci Adv 8: eabk0331 (2022).
  25. Kaneko R, Matsui A, Watanabe M, Harada Y, Kanamori M, Awata N, Kawazoe M, Takao T, Kobayashi Y, Kikutake C, Suyama M, Saito T, Saido TC, *Ito M. “Increased neutrophils in inflammatory bowel disease accelerate the accumulation of amyloid plaques in the mouse model of Alzheimer’s disease.” Inflamm Regenerat 43(1): 20 (2023).
  26. *Koyanagi M, Shen B, Nagata T, Sun L, Wada S, Kamimura S, Kage-Nakadai E, *Terakita A. “High-performance optical control of GPCR signaling by bistable animal opsins MosOpn3 and LamPP in a molecular property-dependent manner.” Proc Natl Acad. Sci U S A 119: e2204341119 (2022).
  27. Imaizumi K, Ideno H, Sato T, Morimoto S, *Okano H. “Pathogenic Mutation of TDP-43 Impairs RNA Processing in a Cell Type-Specific Manner: Implications for the Pathogenesis of ALS/FTLD.” eNeuro 9 (2022).
  28. Kogure YS, Muraoka H, Koizumi WC, Gelin-Alessi R, Godard B, Oka K, Heisenberg CP, *Hotta K. “Admp regulates tail bending by controlling ventral epidermal cell polarity via phosphorylated myosin localization in Ciona.” Development 149: dev200215 (2022).
  29. Matsushita N, Nishizawa K, Kato S, Iguchi Y, Fukabori R, *Takeuchi K, *Kobayashi K “Catecholaminergic cell type-specific expression of Cre recombinase in knock-in transgenic rats generated by the Combi-CRISPR technology.” J Neurosci Method 381: 109707 (2022).
  30. Inami S1,Sato T1, Kurata Y, Suzuki Y, Kitamoto T, and *Sakai T. “Consolidation and maintenance of long-term memory involves dual functions of the developmental regulator Apterous in clock neurons and mushroom bodies in the Drosophila brain.” PLoS Biol 19: e3001459 (2021).
  31. Yoshiko K, Kato K, Iida H, Teramoto M, Kawamura A, Watanabe Y, Nunome M, Nakano M, Matsuda Y, Sato Y, Mizuno H, Iwasato T, Ishii Y, *Kondoh H. “Live imaging of avian epiblast and anterior mesendoderm grafting reveals the complexity of cell dynamics during early brain development.” Development149: dev199999 (2022).
  32. Kanazawa Y, *Omotehara T, Nakata H, Hirashima T, Itoh M “Three-dimensional analysis and in vivo imaging for sperm release and transport in the murine seminiferous tubule.” Reproduction 164: 9-18 (2022).
  33. Itami C, Uesaka N, Huang JY, Lu HC, Sakimura K, Kano M, Kimura F. “Endocannabinoid-dependent formation of columnar axonal projection in the mouse cerebral cortex.” Proc Natl Acad Sci USA 119: e2122700119 (2022).