Original Papers

A01-1 

  • Ali A, Abouleila Y, Shimizu Y, Hiyama E, Watanabe TM, Yanagida T, Germond A
    “Single-Cell Screening of Tamoxifen Abundance and Effect Using Mass Spectrometry and Raman-Spectroscopy”
    Anal Chem, 91(4):2710, 2019
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30664349
  • Shima T, Morikawa M, Kaneshiro J, Kambara T, Kamimura S, Yagi T, Iwamoto H, Uemura S, “Shigematsu H, Shirouzu M, Ichimura T, Watanabe TM, Nitta R, Okada Y, Hirokawa N
    “Kinesin-binding-triggered conformation switching of microtubules contributes to polarized transport ”
    J Cell Biol, 217(12):4164-4183, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30297389
  • Germond A, Ichimura T, Horinouchi T, Fujita H, Furusawa C, Watanabe TM
    “Raman spectral signature reflects transcriptomic features of antibiotic resistance in Escherichia coli”
    Commun Biol, 1:85, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30271966
  • Okamoto K, Germond A, Fujita H, Furusawa C, Okada Y, Watanabe TM
    “Single cell analysis reveals a biophysical aspect of collective cell-state transition in embryonic stem cell differentiation”
    Sci Rep, 8(1):11965, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30097661
  • Germond A, Ichimura T, Chiu LD, Fujita K, Watanabe TM, Fujita H
    “Cell type discrimination based on image features of molecular component distribution”
    Sci Rep, 8(1):11726, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30082723
  • Panina Y, Germond A, Masui S, Watanabe TM
    “Validation of Common Housekeeping Genes as Reference for qPCR Gene Expression Analysis During iPS Reprogramming Process”
    Sci Rep, 8(1):8716, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29880849
  • Shiina T, Toi M, Yagi T
    “Development and clinical translation of photoacoustic mammography”
    Biomed Eng Lett, 8(2):157-165, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=3060320

A01-2

  • Sato R, Kawashima R, Trinh MDL, Nakano M, Nagai T, Masuda S
    “Significance of PGR5-dependent cyclic electron flow for optimizing the rate of ATP synthesis and consumption in Arabidopsis chloroplasts”
    Photosynth Res, 139(1-3):359-365, 2019
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29916043
  • Nezu A, Morita T, Nagai T, Tanimura A
    “Simultaneous monitoring of Ca2+ responses and salivary secretion in live animals reveals a threshold intracellular Ca2+ concentration for salivation”
    Exp Physiol, 104(1):61-69, 2019
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30367746
  • Shinoda H, Ma Y, Nakashima R, Sakurai K, Matsuda T, Nagai T
    “Acid-Tolerant Monomeric GFP from Olindias Formosa”
    Cell Chem Biol, 25(3):330-338.e7, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29290624
  • Maeshima K, Matsuda T, Shindo Y, Imamura H, Tamura S, Imai R, Kawakami S, Nagashima , Soga T, Noji H, Oka K, Nagai T
    “A Transient Rise in Free Mg2+ Ions Released from ATP-Mg Hydrolysis Contributes to Mitotic Chromosome Condensation”
    Curr Biol, 28(3):444-451.e6, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29358072
  • Kushida Y, Arai Y, Shimono K, Nagai T
    “Biomimetic Chemical Sensing by Fluorescence Signals Using a Virus-like Particle-Based Platform”
    ACS Sens, 3(1):87-92, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29256249
  • Wazawa T, Arai Y, Kawahara Y, Takauchi H, Washio T, Nagai T
    “Highly biocompatible super-resolution fluorescence imaging using the fast photoswitching fluorescent protein Kohinoor and SPoD-ExPAN with Lp-regularized image reconstruction”
    Microscopy (Oxf), 67(2):89-98, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29409007
  • Ohta Y, Furuta T, Nagai T, Horikawa K
    “Red fluorescent cAMP indicator with increased affinity and expanded dynamic range”
    Sci Rep, 8(1):1866, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29382930
  • Hossain MN, Suzuki K, Iwano M, Matsuda T, Nagai T
    “Bioluminescent Low-Affinity Ca2+ Indicator for ER with Multicolor Calcium Imaging in Single Living Cells”
    ACS Chem Biol, 13(7):1862-1871, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29494125
  • Hara-Kuge S, Nishihara T, Matsuda T, Kitazono T, Teramoto T, Nagai T, Ishihara T
    “An improved inverse-type Ca2+ indicator can detect putative neuronal inhibition in Caenorhabditis elegans by increasing signal intensity upon Ca2+ decrease”
    PLoS One, 13(4):e0194707, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29694380
  • Riani YD, Matsuda T, Takemoto K, Nagai T
    “Green monomeric photosensitizing fluorescent protein for photo-inducible protein inactivation and cell ablation”
    BMC Biol, 16(1):50, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29712573
  • Suzuki K, Onishi T, Nakada C, Takei S, Daniels MJ, Nakano M, Matsuda T, Nagai T
    “Uninterrupted monitoring of drug effects in human-induced pluripotent stem cell-derived cardiomyocytes with bioluminescence Ca2+ microscopy”
    BMC Res Notes, 11(1):313, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29776438
  • Komatsu N, Terai K, Imanishi A, Kamioka Y, Sumiyama K, Jin T, Okada Y, Nagai T, Matsuda M
    “A platform of BRET-FRET hybrid biosensors for optogenetics, chemical screening, and in vivo imaging”
    Sci Rep, 8(1):8984, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29895862
  • Arai Y, Takauchi H, Ogami Y, Fujiwara S, Nakano M, Matsuda T, Nagai T
    “Spontaneously Blinking Fluorescent Protein for Simple Single Laser Super-Resolution Live Cell Imaging”
    ACS Chem Biol, 13(8):1938-1943, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29963852
  • Shinoda H, Shannon M, Nagai T
    “Fluorescent Proteins for Investigating Biological Events in Acidic Environments”
    Int J Mol Sci, 19(6). pii: E1548, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29789517
  • Li Q, Yoshimura H, Komiya M, Tajiri K, Uesugi M, Hata Y, Ozawa T
    “A robust split-luciferase-based cell fusion screening for discovering myogenesis-promoting molecules”
    Analyst, 143(14):3472-3480, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29944152
  • Pavlou A, Yoshimura H, Aono S, Pinakoulaki E
    “Protein Dynamics of the Sensor Protein HemAT as Probed by Time-Resolved Step-Scan FTIR Spectroscopy”
    Biophys J, 114(3):584-591, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29414704
  • Takenouchi O, Yoshimura H, Ozawa T
    “Unique Roles of β-Arrestin in GPCR Trafficking Revealed by Photoinducible Dimerizers”
    Sci Rep, 8(1):677, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29330504
  • Yoshimura H
    “Live Cell Imaging of Endogenous RNAs Using Pumilio Homology Domain Mutants: Principles and Applications”
    Biochemistry, 57(2):200-208, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29164876
  • Yoshimura H, Ozawa T
    “Real-Time Fluorescence Imaging of Single-Molecule Endogenous Noncoding RNA in Living Cells”
    Methods Mol Biol, 1649:337-347,2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29130208

A01-3

  • Miyamoto C, Kojo S, Yamashita M, Moro K, Lacaud G, Shiroguchi K, Taniuchi I, Ebihara T
    “Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation”
    Nat Commun,10(1):447, 2019
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30683858

A02-1

  • Imakubo M, Takayama J, Onami S
    “Improvement and evaluation of a mathematical model for fertilization calucium waves in Ceanorhabditis elegans ”
    IPSJ Transactions on Bioinformatics, 11: 24-30, 2018
    https://doi.org/10.2197/ipsjtbio.11.24
  • Onoue Y, Kyoda K, Kioka M, Baba K, Onami S, Koyamada K
    “Development of an integrated visualization system for phenotype character networks”
    IEEE Pacific Visualization Symposium (PacificVis 2018): 21-25, 2018
    https://doi.org/10.1109/PacificVis.2018.00012

A03-1

  • Bannai H, Hirose M, Niwa F, Mikoshiba, K
    “Dissection of Local Ca2+ Signals in Cultured Cells by Membrane-targeted Ca2+ Indicators”
    J Vis Exp, 145: e59246, 2019
  • Hiroshima M, Pack CG, Kaizu K, Takahashi K, Ueda M, Sako Y
    “Transient Acceleration of Epidermal Growth Factor Receptor Dynamics Produces Higher-Order Signaling Clusters”
    J Mol Biol, 430(9):1386-1401,2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29505756
  • Yasui M, Hiroshima M, Kozuka J, Sako Y, Ueda M
    “Automated single-molecule imaging in living cells”
    Nat Commun, 9(1):3061, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30076305
  • Yanagawa M, Hiroshima M, Togashi Y, Abe M, Yamashita T, Shichida Y, Murata M, Ueda M, Sako Y
    “Single-molecule diffusion-based estimation of ligand effects on G protein-coupled receptors”
    Sci Signal, 11(548). pii: eaao1917, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30228224
  • Bannai H
    “Molecular membrane dynamics: Insights into synaptic function and neuropathological disease”
    Neurosci Res, 129: 47-56, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/28826905

A03-2

  • Morishima M, Horikawa K, Funaki M
    “Cardiomyocytes cultured on mechanically compliant substrates, but not on conventional culture devices, exhibit prominent mitochondrial dysfunction due to reactive oxygen species and insulin resistance under high glucose”
    PLoS One, 13(8):e0201891,2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30138395
  • Tanihara F, Hirata M, Nguyen NT, Le QA, Hirano T, Takemoto T, Nakai M, Fuchimoto DI, Otoi T
    “Generation of PDX-1 mutant porcine blastocysts by introducing CRISPR/Cas9-system into porcine zygotes via electroporation”
    Anim Sci J, 90(1):55-61, 2019
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30368976
  • Tanihara F, Hirata M, Nguyen NT, Le QA, Hirano T, Takemoto T, Nakai M, Fuchimoto DI, Otoi T
    “Generation of a TP53-modified porcine cancer model by CRISPR/Cas9-mediated gene modification in porcine zygotes via electroporation”
    PLoS One, 13(10):e0206360, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30352075
  • Harada A, Maehara K, Ono Y, Taguchi H, Yoshioka K, Kitajima Y, Xie Y, Sato Y, Iwasaki T, “Nogami J, Okada S, Komatsu T, Semba Y, Takemoto T, Kimura H, Kurumizaka H, Ohkawa Y
    Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration”
    Nat Commun, 9(1):1400, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29643389
  • Nishio K, Tanihara F, Nguyen TV, Kunihara T, Nii M, Hirata M, Takemoto T, Otoi T
    “Effects of voltage strength during electroporation on the development and quality of in vitro-produced porcine embryos”
    Reprod Domest Anim, 53(2):313-318, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29135047

A03-3

  • Li J, Hashimoto H, Meltzer HY
    “Association of Serotonin2c Receptor Polymorphisms With Antipsychotic Drug Response in Schizophrenia”
    Front Psychiatry, 10:58, 2019
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30828307
  • Ivic I, Balasko M, Fulop BD, Hashimoto H, Toth G, Tamas A, Juhasz T, Koller A, Reglodi D, Solymár M
    “VPAC1 receptors play a dominant role in PACAP-induced vasorelaxation in female mice”
    PLoS One, 14(1):e0211433, 2019
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30682157
  • Kawase H, Ago Y, Naito M, Higuchi M, Hara Y, Hasebe S, Tsukada S, Kasai A, Nakazawa T, Mishina T, Kouji H, Takuma K, Hashimoto H
    “mS-11, a mimetic of the mSin3-binding helix in NRSF, ameliorates social interaction deficits in a prenatal valproic acid-induced autism mouse model”
    Pharmacol Biochem Behav, 176:1-5, 2019
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30419271
  • Nishitani N, Nagayasu K, Asaoka N, Yamashiro M, Andoh C, Nagai Y, Kinoshita H, Kawai H, Shibui N, Liu B, Hewinson J, Shirakawa H, Nakagawa T, Hashimoto H, Kasparov S, Kaneko S
    “Manipulation of dorsal raphe serotonergic neurons modulates active coping to inescapable stress and anxiety-related behaviors in mice and rats”
    Neuropsychopharmacology,
    44(4):721-732, 2019
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30377380

A03-4

  • Maeda TK, Sugiura D, Okazaki IM, Maruhashi T, Okazaki T
    “Atypical motifs in the cytoplasmic region of the inhibitory immune co-receptor LAG-3 inhibit T cell activation”
    J Biol Chem, RA119.007455, 2019
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30760527
  • Mizuno R, Maruhashi T, Sugiura D, Shimizu K, Watada M, Okazaki IM, Okazaki T
    “PD-1 efficiently inhibits T cell activation even in the presence of co-stimulation through CD27 and GITR”
    Biochem Biophys Res Commun, S0006-291X(19)30183-4, 2019
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30771904
  • Takeuchi A, Ozawa M, Kanda Y, Kozai M, Ohigashi I, Kurosawa Y, Rahman MA, Kawamura T, “Shichida Y, Umemoto E, Miyasaka M, Ludewig B, Takahama Y, Nagasawa T, Katakai T
    A Distinct Subset of Fibroblastic Stromal Cells Constitutes the Cortex-Medulla Boundary Subcompartment of the Lymph Node”
    Front Immunol, 9:2196, 2019
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30333825
  • Maruhashi T, Okazaki IM, Sugiura D, Takahashi S, Maeda TK, Shimizu K, Okazaki T
    “LAG-3 inhibits the activation of CD4+ T cells that recognize stable pMHCII through its conformation-dependent recognition of pMHCII”
    Nat Immunol, 19(12):1415-1426,2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30349037
  • Bogdanova D, Takeuchi A, Ozawa M, Kanda Y, Rahman MA, Ludewig B, Kinashi T, Katakai T
    “Essential Role of Canonical NF-κB Activity in the Development of Stromal Cell Subsets in Secondary Lymphoid Organs”
    J Immunol, 201(12): 3580-3586, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=30397032
  • Kanda Y, Takeuchi A, Ozawa M, Kurosawa Y, Kawamura T, Bogdanova D, Iioka H, Kondo E, Kitazawa Y, Ueta H, Matsuno K, Kinashi T, Katakai T
    “Visualizing the Rapid and Dynamic Elimination of Allogeneic T Cells in Secondary Lymphoid Organs”
    J Immunol,201(3):1062-1072, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29925676
  • Katakai T
    “Live Imaging of Interstitial T Cell Migration Using Lymph Node Slices”
    Methods Mol Biol, 1763:29-42, 2018
    https://www.ncbi.nlm.nih.gov/pubmed/?term=29476486