Anaysis of singularity cell in the developmental pattern formation
Developmental pattern formation is the excellent model of singularity phenomena. By introducing newly developed trans-scale imaging, we will investigate the onset dynamics of collective signaling in the population of social amoeba (>10,000 cells) at 1-cell resolution. Our goals are to address how small number of cell controls the population dynamics, and how such singularity cells emerge in initially indistinguishable population. We will also develop strategies for controlling and predicting population dynamics by focusing on the function of small number of singularity cells.